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NLK-mediated phosphorylation of HDAC1 negatively regulates Wnt signaling

The Wnt signaling pathway is essential in regulating various cellular processes. Different mechanisms of inhibition for Wnt signaling have been proposed. Besides β-catenin degradation through the proteasome, nemo-like kinase (NLK) is another molecule that is known to negatively regulate Wnt signalin...

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Detalles Bibliográficos
Autores principales: Masoumi, Katarzyna Chmielarska, Daams, Renée, Sime, Wondossen, Siino, Valentina, Ke, Hengning, Levander, Fredrik, Massoumi, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231902/
https://www.ncbi.nlm.nih.gov/pubmed/27903773
http://dx.doi.org/10.1091/mbc.E16-07-0547