Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens

PURPOSE: Severing corneal nerves during corneal transplantation does not affect first corneal transplants, but abolishes immune privilege of subsequent corneal allografts. This abrogation of immune privilege is attributable to the disabling of T regulatory cells (T regs) induced by corneal transplan...

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Detalles Bibliográficos
Autores principales: Mo, Juan, Neelam, Sudha, Mellon, Jessamee, Brown, Joseph R., Niederkorn, Jerry Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231905/
https://www.ncbi.nlm.nih.gov/pubmed/28114571
http://dx.doi.org/10.1167/iovs.16-20601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231905/
https://www.ncbi.nlm.nih.gov/pubmed/28114571
http://dx.doi.org/10.1167/iovs.16-20601

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