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Effect of Corneal Nerve Ablation on Immune Tolerance Induced by Corneal Allografts, Oral Immunization, or Anterior Chamber Injection of Antigens
PURPOSE: Severing corneal nerves during corneal transplantation does not affect first corneal transplants, but abolishes immune privilege of subsequent corneal allografts. This abrogation of immune privilege is attributable to the disabling of T regulatory cells (T regs) induced by corneal transplan...
Autores principales: | Mo, Juan, Neelam, Sudha, Mellon, Jessamee, Brown, Joseph R., Niederkorn, Jerry Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231905/ https://www.ncbi.nlm.nih.gov/pubmed/28114571 http://dx.doi.org/10.1167/iovs.16-20601 |
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