One-Way Allosteric Communication between the Two Disulfide Bonds in Tissue Factor

Tissue factor (TF) is a transmembrane glycoprotein that plays distinct roles in the initiation of extrinsic coagulation cascade and thrombosis. TF contains two disulfide bonds, one each in the N-terminal and C-terminal extracellular domains. The C-domain disulfide, Cys186-Cys209, has a −RHStaple con...

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Detalles Bibliográficos
Autores principales: Zhou, Beifei, Hogg, Philip J., Gräter, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2017
Materias:
Proteins
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5232894/
https://www.ncbi.nlm.nih.gov/pubmed/28076818
http://dx.doi.org/10.1016/j.bpj.2016.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5232894/
https://www.ncbi.nlm.nih.gov/pubmed/28076818
http://dx.doi.org/10.1016/j.bpj.2016.12.003

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