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Hippocalcin Promotes Neuronal Differentiation and Inhibits Astrocytic Differentiation in Neural Stem Cells

Hippocalcin (HPCA) is a calcium-binding protein that is restricted to nervous tissue and contributes to neuronal activity. Here we report that, in addition to inducing neurogenesis, HPCA inhibits astrocytic differentiation of neural stem cells. It promotes neurogenesis by regulating protein kinase C...

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Detalles Bibliográficos
Autores principales: Park, Shin-Young, Yoon, Sung Nyo, Kang, Min-Jeong, Lee, YunYoung, Jung, Sung Jun, Han, Joong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233403/
https://www.ncbi.nlm.nih.gov/pubmed/28017654
http://dx.doi.org/10.1016/j.stemcr.2016.11.009