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Direct Reprogramming of Mouse Fibroblasts toward Leydig-like Cells by Defined Factors
Leydig cells (LCs) play crucial roles in producing testosterone, and their dysfunction leads to male hypogonadism. LC transplantation is a promising alternative therapy for male hypogonadism. However, the source of LCs limits this strategy for clinical applications. Here, we report our success in re...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233410/ https://www.ncbi.nlm.nih.gov/pubmed/28017657 http://dx.doi.org/10.1016/j.stemcr.2016.11.010 |