Direct Reprogramming of Mouse Fibroblasts toward Leydig-like Cells by Defined Factors

Leydig cells (LCs) play crucial roles in producing testosterone, and their dysfunction leads to male hypogonadism. LC transplantation is a promising alternative therapy for male hypogonadism. However, the source of LCs limits this strategy for clinical applications. Here, we report our success in re...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Li, Ziyi, Wu, Xupeng, Chen, Haolin, Xu, Wenting, Xiang, Qi, Zhang, Qihao, Chen, Jie, Ge, Ren-Shan, Su, Zhijian, Huang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233410/
https://www.ncbi.nlm.nih.gov/pubmed/28017657
http://dx.doi.org/10.1016/j.stemcr.2016.11.010

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