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Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility

Loss-of-function mutations in the cytosine-5 RNA methylase NSUN2 cause neurodevelopmental disorders in humans, yet the underlying cellular processes leading to the symptoms that include microcephaly remain unclear. Here, we show that NSUN2 is expressed in early neuroepithelial progenitors of the dev...

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Detalles Bibliográficos
Autores principales: Flores, Joana V., Cordero-Espinoza, Lucía, Oeztuerk-Winder, Feride, Andersson-Rolf, Amanda, Selmi, Tommaso, Blanco, Sandra, Tailor, Jignesh, Dietmann, Sabine, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233436/
https://www.ncbi.nlm.nih.gov/pubmed/28041877
http://dx.doi.org/10.1016/j.stemcr.2016.11.014