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Epigenetic Modifiers Facilitate Induction and Pluripotency of Porcine iPSCs

Inadequate silencing of exogenous genes represents a major obstacle to complete epigenetic reprogramming of porcine-induced pluripotent stem cells (piPSCs) by conventional pluripotency transcription factors (OSKM). We tested the hypothesis that epigenetic modification by active DNA or histone demeth...

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Detalles Bibliográficos
Autores principales: Mao, Jian, Zhang, Qian, Deng, Wei, Wang, Hua, Liu, Kai, Fu, Haifeng, Zhao, Qiang, Wang, Xumin, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233437/
https://www.ncbi.nlm.nih.gov/pubmed/28041878
http://dx.doi.org/10.1016/j.stemcr.2016.11.013