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A Functional Bioluminescent Zebrafish Screen for Enhancing Hematopoietic Cell Homing

To discover small molecules that modulate hematopoietic cell homing after adoptive transfer, we created a transgenic zebrafish expressing firefly luciferase downstream of the ubiquitin promoter (ubi:luc) to serve as a hematopoietic donor. Bioluminescence imaging (BLI) was used to detect and follow u...

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Detalles Bibliográficos
Autores principales: Astuti, Yuliana, Kramer, Ashley C., Blake, Amanda L., Blazar, Bruce R., Tolar, Jakub, Taisto, Mandy E., Lund, Troy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233450/
https://www.ncbi.nlm.nih.gov/pubmed/28041876
http://dx.doi.org/10.1016/j.stemcr.2016.12.004