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Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy

Mitophagy is an essential intracellular process that eliminates dysfunctional mitochondria and maintains cellular homeostasis. Mitophagy is regulated by the post-translational modification of mitophagy receptors. Fun14 domain-containing protein 1 (FUNDC1) was reported to be a new receptor for hypoxi...

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Detalles Bibliográficos
Autores principales: Lv, Mengqi, Wang, Chongyuan, Li, Fudong, Peng, Junhui, Wen, Bin, Gong, Qingguo, Shi, Yunyu, Tang, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233613/
https://www.ncbi.nlm.nih.gov/pubmed/27757847
http://dx.doi.org/10.1007/s13238-016-0328-8