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Heterogeneous patterns of DNA methylation-based field effects in histologically normal prostate tissue from cancer patients

Prostate cancer (PC) diagnosis is based on histological evaluation of prostate needle biopsies, which have high false negative rates. Here, we investigated if cancer-associated epigenetic field effects in histologically normal prostate tissue may be used to increase sensitivity for PC. We focused on...

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Detalles Bibliográficos
Autores principales: Møller, Mia, Strand, Siri Hundtofte, Mundbjerg, Kamilla, Liang, Gangning, Gill, Inderbir, Haldrup, Christa, Borre, Michael, Høyer, Søren, Ørntoft, Torben Falck, Sørensen, Karina Dalsgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233981/
https://www.ncbi.nlm.nih.gov/pubmed/28084441
http://dx.doi.org/10.1038/srep40636