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Heterogeneous patterns of DNA methylation-based field effects in histologically normal prostate tissue from cancer patients
Prostate cancer (PC) diagnosis is based on histological evaluation of prostate needle biopsies, which have high false negative rates. Here, we investigated if cancer-associated epigenetic field effects in histologically normal prostate tissue may be used to increase sensitivity for PC. We focused on...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233981/ https://www.ncbi.nlm.nih.gov/pubmed/28084441 http://dx.doi.org/10.1038/srep40636 |