Increased Renal Clearance of Rocuronium Compensates for Chronic Loss of Bile Excretion, via upregulation of Oatp2

Requirement for rocuronium upon surgery changes only minimally in patients with end-stage liver diseases. Our study consisted of both human and rat studies to explore the reason. The reduction rate of rocuronium infusion required to maintain neuromuscular blockade during the anhepatic phase (relativ...

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Detalles Bibliográficos
Autores principales: Wang, Long, Zhou, Mai-Tao, Chen, Cai-Yang, Yin, Wen, Wen, Da-Xiang, Cheung, Chi-Wai, Yang, Li-Qun, Yu, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233986/
https://www.ncbi.nlm.nih.gov/pubmed/28084414
http://dx.doi.org/10.1038/srep40438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233986/
https://www.ncbi.nlm.nih.gov/pubmed/28084414
http://dx.doi.org/10.1038/srep40438

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