Optogenetic Control of Heart Rhythm by Selective Stimulation of Cardiomyocytes Derived from Pnmt(+) Cells in Murine Heart

In the present study, channelrhodopsin 2 (ChR2) was specifically introduced into murine cells expressing the Phenylethanolamine n-methyltransferase (Pnmt) gene, which encodes for the enzyme responsible for conversion of noradrenaline to adrenaline. The new murine model enabled the identification of...

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Detalles Bibliográficos
Autores principales: Wang, Yanwen, Lin, Wee Khang, Crawford, William, Ni, Haibo, Bolton, Emma L., Khan, Huma, Shanks, Julia, Bub, Gil, Wang, Xin, Paterson, David J., Zhang, Henggui, Galione, Antony, Ebert, Steven N., Terrar, Derek A., Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234027/
https://www.ncbi.nlm.nih.gov/pubmed/28084430
http://dx.doi.org/10.1038/srep40687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234027/
https://www.ncbi.nlm.nih.gov/pubmed/28084430
http://dx.doi.org/10.1038/srep40687

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