Targeting pathogen metabolism without collateral damage to the host

The development of drugs that can inactivate disease-causing cells (e.g. cancer cells or parasites) without causing collateral damage to healthy or to host cells is complicated by the fact that many proteins are very similar between organisms. Nevertheless, due to subtle, quantitative differences be...

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Detalles Bibliográficos
Autores principales: Haanstra, Jurgen R., Gerding, Albert, Dolga, Amalia M., Sorgdrager, Freek J. H., Buist-Homan, Manon, du Toit, François, Faber, Klaas Nico, Holzhütter, Hermann-Georg, Szöör, Balázs, Matthews, Keith R., Snoep, Jacky L., Westerhoff, Hans V., Bakker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234033/
https://www.ncbi.nlm.nih.gov/pubmed/28084422
http://dx.doi.org/10.1038/srep40406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234033/
https://www.ncbi.nlm.nih.gov/pubmed/28084422
http://dx.doi.org/10.1038/srep40406

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