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Targeting pathogen metabolism without collateral damage to the host
The development of drugs that can inactivate disease-causing cells (e.g. cancer cells or parasites) without causing collateral damage to healthy or to host cells is complicated by the fact that many proteins are very similar between organisms. Nevertheless, due to subtle, quantitative differences be...
Autores principales: | Haanstra, Jurgen R., Gerding, Albert, Dolga, Amalia M., Sorgdrager, Freek J. H., Buist-Homan, Manon, du Toit, François, Faber, Klaas Nico, Holzhütter, Hermann-Georg, Szöör, Balázs, Matthews, Keith R., Snoep, Jacky L., Westerhoff, Hans V., Bakker, Barbara M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234033/ https://www.ncbi.nlm.nih.gov/pubmed/28084422 http://dx.doi.org/10.1038/srep40406 |
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