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De novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes

The interaction between the bone marrow microenvironment and malignant hematopoietic cells can result in the protection of leukemia cells from chemotherapy in both myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). We, herein, characterized the changes in cytokine expression and the f...

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Detalles Bibliográficos
Autores principales: Lopes, Matheus Rodrigues, Pereira, João Kleber Novais, de Melo Campos, Paula, Machado-Neto, João Agostinho, Traina, Fabiola, Saad, Sara T. Olalla, Favaro, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234038/
https://www.ncbi.nlm.nih.gov/pubmed/28084439
http://dx.doi.org/10.1038/srep40707