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Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

On the basis of nascent transcript sequencing, it has been postulated but never demonstrated that transcriptional pausing at translation start sites is important for gene regulation. Here we show that the Escherichia coli thiamin pyrophosphate (TPP) thiC riboswitch contains a regulatory pause site i...

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Detalles Bibliográficos
Autores principales: Chauvier, Adrien, Picard-Jean, Frédéric, Berger-Dancause, Jean-Christophe, Bastet, Laurène, Naghdi, Mohammad Reza, Dubé, Audrey, Turcotte, Pierre, Perreault, Jonathan, Lafontaine, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234074/
https://www.ncbi.nlm.nih.gov/pubmed/28071751
http://dx.doi.org/10.1038/ncomms13892