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Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation
On the basis of nascent transcript sequencing, it has been postulated but never demonstrated that transcriptional pausing at translation start sites is important for gene regulation. Here we show that the Escherichia coli thiamin pyrophosphate (TPP) thiC riboswitch contains a regulatory pause site i...
Autores principales: | Chauvier, Adrien, Picard-Jean, Frédéric, Berger-Dancause, Jean-Christophe, Bastet, Laurène, Naghdi, Mohammad Reza, Dubé, Audrey, Turcotte, Pierre, Perreault, Jonathan, Lafontaine, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234074/ https://www.ncbi.nlm.nih.gov/pubmed/28071751 http://dx.doi.org/10.1038/ncomms13892 |
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