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Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation

BACKGROUND: DNA methylation is a major epigenetic modification, playing a crucial role in the development and differentiation of higher organisms. DNA methylation is also known to regulate transcription by gene repression. Various developmental genes such as c-mos, HoxB5, Sox11, and Sry show tissue-...

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Detalles Bibliográficos
Autores principales: Sinha, Puja, Singh, Kiran, Sachan, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234095/
https://www.ncbi.nlm.nih.gov/pubmed/28081716
http://dx.doi.org/10.1186/s12867-016-0078-4