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Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation
BACKGROUND: DNA methylation is a major epigenetic modification, playing a crucial role in the development and differentiation of higher organisms. DNA methylation is also known to regulate transcription by gene repression. Various developmental genes such as c-mos, HoxB5, Sox11, and Sry show tissue-...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234095/ https://www.ncbi.nlm.nih.gov/pubmed/28081716 http://dx.doi.org/10.1186/s12867-016-0078-4 |