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Contaminants in commercial preparations of ‘purified’ small leucine-rich proteoglycans may distort mechanistic studies

The present study reports the perplexing results that came about because of seriously impure commercially available reagents. Commercial reagents and chemicals are routinely ordered by scientists and expected to have been rigorously assessed for their purity. Unfortunately, we found this assumption...

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Detalles Bibliográficos
Autores principales: Brown, Sharon J., Fuller, Heidi R., Jones, Philip, Caterson, Bruce, Shirran, Sally L., Botting, Catherine H., Roberts, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234103/
https://www.ncbi.nlm.nih.gov/pubmed/27994047
http://dx.doi.org/10.1042/BSR20160465