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Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide

BACKGROUND: Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E(2) (PGE(2)) is one of the products of COX activity. PGE(2) has pleiotropic actions depending on the activation of specific E-type prostanoid EP1-4 receptors. We investigated the involvement of PGE(2) a...

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Detalles Bibliográficos
Autores principales: Bonfill-Teixidor, Ester, Otxoa-de-Amezaga, Amaia, Font-Nieves, Miriam, Sans-Fons, M. Glòria, Planas, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234110/
https://www.ncbi.nlm.nih.gov/pubmed/28086956
http://dx.doi.org/10.1186/s12974-016-0780-7