Berberine inhibits enterovirus 71 replication by downregulating the MEK/ERK signaling pathway and autophagy

BACKGROUND: The MEK-ERK signaling pathway and autophagy play an important role for enterovirus71(EV71) replication. Inhibition of MEK-ERK signaling pathway and autophagy is shown to impair EV71 replication. Berberine (BBR), an isoquinoline alkaloid isolated from Berberis vulgaris L., has been report...

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Detalles Bibliográficos
Autores principales: Wang, Huiqiang, Li, Ke, Ma, Linlin, Wu, Shuo, Hu, Jin, Yan, Haiyan, Jiang, Jiandong, Li, Yuhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234143/
https://www.ncbi.nlm.nih.gov/pubmed/28081706
http://dx.doi.org/10.1186/s12985-016-0674-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234143/
https://www.ncbi.nlm.nih.gov/pubmed/28081706
http://dx.doi.org/10.1186/s12985-016-0674-4

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