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Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO)
G-protein coupled inwardly rectifying potassium (GIRK) channels are expressed throughout the human body and are an integral part of inhibitory signal transduction pathways. Upon binding of G(βγ) subunits released from G-protein coupled receptors (GPCRs), GIRK channels open and reduce the activity of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234268/ https://www.ncbi.nlm.nih.gov/pubmed/28090283 http://dx.doi.org/10.1039/c5sc04084a |