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Presenilin 2 overexpression is associated with apoptosis in Neuro2a cells
Presenilin 1 (PS1) and PS2 are evolutionarily conserved transmembrane proteins of the aspartyl protease family. Initially, they were reported to be associated with the early onset of familial, early-onset Alzheimer’s disease. PS1 has been implicated in several crucial brain functions including devel...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234515/ https://www.ncbi.nlm.nih.gov/pubmed/28123824 http://dx.doi.org/10.1515/tnsci-2016-0011 |