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A Computational Approach for Identifying Synergistic Drug Combinations

A promising alternative to address the problem of acquired drug resistance is to rely on combination therapies. Identification of the right combinations is often accomplished through trial and error, a labor and resource intensive process whose scale quickly escalates as more drugs can be combined....

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Detalles Bibliográficos
Autores principales: Gayvert, Kaitlyn M., Aly, Omar, Platt, James, Bosenberg, Marcus W., Stern, David F., Elemento, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234777/
https://www.ncbi.nlm.nih.gov/pubmed/28085880
http://dx.doi.org/10.1371/journal.pcbi.1005308