OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo

An abnormal increase in osteoclast differentiation and activation results in various bone-resorptive diseases, including periodontitis, rheumatoid arthritis, and osteoporosis. Chemical compounds containing pyrimidine ring have been shown to regulate a variety of biological processes. Therefore, in o...

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Detalles Bibliográficos
Autores principales: Ihn, Hye Jung, Lee, Taeho, Kim, Ju Ang, Lee, Doohyun, Kim, Nam Doo, Shin, Hong-In, Bae, Yong Chul, Park, Eui Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234796/
https://www.ncbi.nlm.nih.gov/pubmed/28085946
http://dx.doi.org/10.1371/journal.pone.0170159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234796/
https://www.ncbi.nlm.nih.gov/pubmed/28085946
http://dx.doi.org/10.1371/journal.pone.0170159

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