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Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP

The endocrine disruptor bis(2-ethylhexyl) phthalate (DEHP) has been shown to exert adverse effects on the male animal reproductive system. However, its mode of action is unclear and a systematic analysis of its molecular targets is needed. In the present study, we investigated the effects of prenata...

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Detalles Bibliográficos
Autores principales: Stenz, Ludwig, Escoffier, Jessica, Rahban, Rita, Nef, Serge, Paoloni-Giacobino, Ariane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234833/
https://www.ncbi.nlm.nih.gov/pubmed/28085963
http://dx.doi.org/10.1371/journal.pone.0170441