Mechanism of Collaborative Enhancement of Binding of Paired Antibodies to Distinct Epitopes of Platelet Endothelial Cell Adhesion Molecule-1

Monoclonal antibodies (mAbs) directed to extracellular epitopes of human and mouse Platelet Endothelial Cell Adhesion Molecule-1 (CD31 or PECAM-1) stimulate binding of other mAbs to distinct adjacent PECAM-1 epitopes. This effect, dubbed Collaborative Enhancement of Paired Affinity Ligands, or CEPAL...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiseleva, Raisa, Greineder, Colin F., Villa, Carlos H., Hood, Elizabeth D., Shuvaev, Vladimir V., Sun, Jing, Chacko, Ann-Marie, Abraham, Valsamma, DeLisser, Horace M., Muzykantov, Vladimir R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234847/
https://www.ncbi.nlm.nih.gov/pubmed/28085903
http://dx.doi.org/10.1371/journal.pone.0169537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234847/
https://www.ncbi.nlm.nih.gov/pubmed/28085903
http://dx.doi.org/10.1371/journal.pone.0169537

Ejemplares similares