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Glucocorticoid Insensitivity in Virally Infected Airway Epithelial Cells Is Dependent on Transforming Growth Factor-β Activity
Asthma and chronic obstructive pulmonary disease (COPD) exacerbations are commonly associated with respiratory syncytial virus (RSV), rhinovirus (RV) and influenza A virus (IAV) infection. The ensuing airway inflammation is resistant to the anti-inflammatory actions of glucocorticoids (GCs). Viral i...
Autores principales: | Xia, Yuxiu C., Radwan, Asmaa, Keenan, Christine R., Langenbach, Shenna Y., Li, Meina, Radojicic, Danica, Londrigan, Sarah L., Gualano, Rosa C., Stewart, Alastair G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234851/ https://www.ncbi.nlm.nih.gov/pubmed/28046097 http://dx.doi.org/10.1371/journal.ppat.1006138 |
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