Targeted disruption of the orphan receptor Gpr151 does not alter pain-related behaviour despite a strong induction in dorsal root ganglion expression in a model of neuropathic pain

BACKGROUND: Gpr151 is an orphan GPCR whose function is unknown. The restricted pattern of neuronal expression in the habenula, dorsal horn of the spinal cord and dorsal root ganglion plus homology with the galanin family of receptors imply a role in nociception. RESULTS: Real-time quantitative RT-PC...

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Detalles Bibliográficos
Autores principales: Holmes, Fiona E., Kerr, Niall, Chen, Ying-Ju, Vanderplank, Penny, McArdle, Craig A., Wynick, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235321/
https://www.ncbi.nlm.nih.gov/pubmed/27913310
http://dx.doi.org/10.1016/j.mcn.2016.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235321/
https://www.ncbi.nlm.nih.gov/pubmed/27913310
http://dx.doi.org/10.1016/j.mcn.2016.11.010

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