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The RNA Polymerase III Subunit Polr3b Is Required for the Maintenance of Small Intestinal Crypts in Mice

BACKGROUND & AIMS: The continuously self-renewing mammalian intestinal epithelium, with high cellular turnover, depends on adequate protein synthesis for its proliferative capacity. RNA polymerase III activity is related closely to cellular growth and proliferation. Here, we studied the role of...

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Detalles Bibliográficos
Autores principales: Kieckhaefer, Julia E., Lukovac, Sabina, Ye, Diana Z., Lee, Dolim, Beetler, Danielle J., Pack, Michael, Kaestner, Klaus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235342/
https://www.ncbi.nlm.nih.gov/pubmed/28090567
http://dx.doi.org/10.1016/j.jcmgh.2016.08.003