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Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

Mitochondria support synaptic transmission through production of ATP, sequestration of calcium, synthesis of glutamate, and other vital functions. Surprisingly, less than 50% of hippocampal CA1 presynaptic boutons contain mitochondria, raising the question of whether synapses without mitochondria ca...

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Detalles Bibliográficos
Autores principales: Smith, Heather L, Bourne, Jennifer N, Cao, Guan, Chirillo, Michael A, Ostroff, Linnaea E, Watson, Deborah J, Harris, Kristen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235352/
https://www.ncbi.nlm.nih.gov/pubmed/27991850
http://dx.doi.org/10.7554/eLife.15275