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NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans

Transient increases in mitochondrially-derived reactive oxygen species (ROS) activate an adaptive stress response to promote longevity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases produce ROS locally in response to various stimuli, and thereby regulate many cellular processes, but t...

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Detalles Bibliográficos
Autores principales: Ewald, Collin Yvès, Hourihan, John M, Bland, Monet S, Obieglo, Carolin, Katic, Iskra, Moronetti Mazzeo, Lorenza E, Alcedo, Joy, Blackwell, T Keith, Hynes, Nancy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235354/
https://www.ncbi.nlm.nih.gov/pubmed/28085666
http://dx.doi.org/10.7554/eLife.19493