Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development

Inactivation of Brg1 and Brm accelerated lung tumor development, shortened tumor latency, and caused a loss of differentiation. Tumors with Brg1 and/or Brm loss recapitulated the evolution of human lung cancer as observed by the development of local tumor invasion as well as distal tumor metastasis,...

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Detalles Bibliográficos
Autores principales: Marquez-Vilendrer, Stefanie B., Rai, Sudhir K., Gramling, Sarah JB, Lu, Li, Reisman, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235921/
https://www.ncbi.nlm.nih.gov/pubmed/28105457
http://dx.doi.org/10.18632/oncoscience.323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235921/
https://www.ncbi.nlm.nih.gov/pubmed/28105457
http://dx.doi.org/10.18632/oncoscience.323

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