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Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development

Inactivation of Brg1 and Brm accelerated lung tumor development, shortened tumor latency, and caused a loss of differentiation. Tumors with Brg1 and/or Brm loss recapitulated the evolution of human lung cancer as observed by the development of local tumor invasion as well as distal tumor metastasis,...

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Detalles Bibliográficos
Autores principales:	Marquez-Vilendrer, Stefanie B., Rai, Sudhir K., Gramling, Sarah JB, Lu, Li, Reisman, David N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235921/ https://www.ncbi.nlm.nih.gov/pubmed/28105457 http://dx.doi.org/10.18632/oncoscience.323

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