BRG1 and BRM loss selectively impacts RB and P53, respectively: BRG1 and BRM have differential functions in vivo

The SWI/SNF complex is an important regulator of gene expression that functions by interacting with a diverse array of cellular proteins. The catalytic subunits of SWI/SNF, BRG1 and BRM, are frequently lost alone or concomitantly in a range of different cancer types. This loss abrogates SWI/SNF comp...

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Detalles Bibliográficos
Autores principales: Marquez-Vilendrer, Stefanie B., Rai, Sudhir K., Gramling, Sarah JB, Lu, Li, Reisman, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235922/
https://www.ncbi.nlm.nih.gov/pubmed/28105458
http://dx.doi.org/10.18632/oncoscience.333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235922/
https://www.ncbi.nlm.nih.gov/pubmed/28105458
http://dx.doi.org/10.18632/oncoscience.333

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