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Networks of Cultured iPSC-Derived Neurons Reveal the Human Synaptic Activity-Regulated Adaptive Gene Program

Long-term adaptive responses in the brain, such as learning and memory, require synaptic activity-regulated gene expression, which has been thoroughly investigated in rodents. Using human iPSC-derived neuronal networks, we show that the human and the mouse synaptic activity-induced transcriptional p...

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Detalles Bibliográficos
Autores principales: Pruunsild, Priit, Bengtson, C. Peter, Bading, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236011/
https://www.ncbi.nlm.nih.gov/pubmed/28052243
http://dx.doi.org/10.1016/j.celrep.2016.12.018