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Depression of home cage wheel running: a reliable and clinically relevant method to assess migraine pain in rats

BACKGROUND: The development of new anti-migraine treatments is limited by the difficulty inassessing migraine pain in laboratory animals. Depression of activity is one of the few diagnostic criteria formigraine that can be mimicked in rats. The goal of the present study was to test the hypothesis th...

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Detalles Bibliográficos
Autores principales: Kandasamy, Ram, Lee, Andrea T., Morgan, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236037/
https://www.ncbi.nlm.nih.gov/pubmed/28091820
http://dx.doi.org/10.1186/s10194-017-0721-6