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The Importance of l-Arginine:NO:cGMP Pathway in Tolerance to Flunitrazepam in Mice
The goal of the study was to investigate the effects of drugs modifying l-arginine:NO:cGMP pathway on the development of tolerance to flunitrazepam (FNZ)-induced motor impairment in mice. FNZ-induced motor incoordination was assessed on the 1st and 8th days of experiment, using the rotarod and chimn...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236083/ https://www.ncbi.nlm.nih.gov/pubmed/27957675 http://dx.doi.org/10.1007/s12640-016-9688-3 |