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Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease

AIM: To develop a human in vitro model of non-alcoholic fatty liver disease (NAFLD), utilising primary hepatocytes cultured in a three-dimensional (3D) perfused platform. METHODS: Fat and lean culture media were developed to directly investigate the effects of fat loading on primary hepatocytes cult...

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Detalles Bibliográficos
Autores principales: Kostrzewski, Tomasz, Cornforth, Terri, Snow, Sophie A, Ouro-Gnao, Larissa, Rowe, Cliff, Large, Emma M, Hughes, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5236500/
https://www.ncbi.nlm.nih.gov/pubmed/28127194
http://dx.doi.org/10.3748/wjg.v23.i2.204