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Biochemical mechanism underlying hypertriglyceridemia and hepatic steatosis/hepatomegaly induced by acute schisandrin B treatment in mice

BACKGROUND: It has been demonstrated that acute oral administration of schisandrin B (Sch B), an active dibenzocyclooctadiene isolated from Schisandrae Fructus (a commonly used traditional Chinese herb), increased serum and hepatic triglyceride (TG) levels and hepatic mass in mice. The present study...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhao, Jing, Zhou, Shu-Feng, Yu, Zhi-Ling, Wang, Xiao-Yan, Zhu, Pei-Li, Chu, Zhu-Sheng, Pan, Si-Yuan, Xie, Ming, Ko, Kam-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237187/
https://www.ncbi.nlm.nih.gov/pubmed/28086886
http://dx.doi.org/10.1186/s12944-017-0406-9