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Is treatment-resistant schizophrenia categorically distinct from treatment-responsive schizophrenia? a systematic review

BACKGROUND: Schizophrenia is a highly heterogeneous disorder, and around a third of patients are treatment-resistant. The only evidence-based treatment for these patients is clozapine, an atypical antipsychotic with relatively weak dopamine antagonism. It is plausible that varying degrees of respons...

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Detalles Bibliográficos
Autores principales: Gillespie, Amy L., Samanaite, Ruta, Mill, Jonathan, Egerton, Alice, MacCabe, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237235/
https://www.ncbi.nlm.nih.gov/pubmed/28086761
http://dx.doi.org/10.1186/s12888-016-1177-y