The release and trans-synaptic transmission of Tau via exosomes

BACKGROUND: Tau pathology in AD spreads in a hierarchical pattern, whereby it first appears in the entorhinal cortex, then spreads to the hippocampus and later to the surrounding areas. Based on this sequential appearance, AD can be classified into six stages (“Braak stages”). The mechanisms and age...

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Detalles Bibliográficos
Autores principales: Wang, Yipeng, Balaji, Varun, Kaniyappan, Senthilvelrajan, Krüger, Lars, Irsen, Stephan, Tepper, Katharina, Chandupatla, RamReddy, Maetzler, Walter, Schneider, Anja, Mandelkow, Eckhard, Mandelkow, Eva-Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237256/
https://www.ncbi.nlm.nih.gov/pubmed/28086931
http://dx.doi.org/10.1186/s13024-016-0143-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237256/
https://www.ncbi.nlm.nih.gov/pubmed/28086931
http://dx.doi.org/10.1186/s13024-016-0143-y

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