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External validation of a clinical decision rule: we need events in a population in order to rule them out!

We respond to the Lorton et al. article on external validation of the PECARN study. With an event rate of only 0.6%, we believe that their study failed to confirm the safety of this rule. Such a low number of events should call for caution when interpreting the results of diagnostic tests.

Detalles Bibliográficos
Autores principales: Freund, Yonathan, Philippon, Anne-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237260/
https://www.ncbi.nlm.nih.gov/pubmed/28086985
http://dx.doi.org/10.1186/s13049-016-0346-9