External validation of a clinical decision rule: we need events in a population in order to rule them out!

We respond to the Lorton et al. article on external validation of the PECARN study. With an event rate of only 0.6%, we believe that their study failed to confirm the safety of this rule. Such a low number of events should call for caution when interpreting the results of diagnostic tests.

Detalles Bibliográficos
Autores principales: Freund, Yonathan, Philippon, Anne-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237260/
https://www.ncbi.nlm.nih.gov/pubmed/28086985
http://dx.doi.org/10.1186/s13049-016-0346-9
_version_ 1782495499279925248
author Freund, Yonathan
Philippon, Anne-Laure
author_facet Freund, Yonathan
Philippon, Anne-Laure
author_sort Freund, Yonathan
collection PubMed
description We respond to the Lorton et al. article on external validation of the PECARN study. With an event rate of only 0.6%, we believe that their study failed to confirm the safety of this rule. Such a low number of events should call for caution when interpreting the results of diagnostic tests.
format Online
Article
Text
id pubmed-5237260
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-52372602017-01-18 External validation of a clinical decision rule: we need events in a population in order to rule them out! Freund, Yonathan Philippon, Anne-Laure Scand J Trauma Resusc Emerg Med Letter to the Editor We respond to the Lorton et al. article on external validation of the PECARN study. With an event rate of only 0.6%, we believe that their study failed to confirm the safety of this rule. Such a low number of events should call for caution when interpreting the results of diagnostic tests. BioMed Central 2017-01-13 /pmc/articles/PMC5237260/ /pubmed/28086985 http://dx.doi.org/10.1186/s13049-016-0346-9 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Freund, Yonathan
Philippon, Anne-Laure
External validation of a clinical decision rule: we need events in a population in order to rule them out!
title External validation of a clinical decision rule: we need events in a population in order to rule them out!
title_full External validation of a clinical decision rule: we need events in a population in order to rule them out!
title_fullStr External validation of a clinical decision rule: we need events in a population in order to rule them out!
title_full_unstemmed External validation of a clinical decision rule: we need events in a population in order to rule them out!
title_short External validation of a clinical decision rule: we need events in a population in order to rule them out!
title_sort external validation of a clinical decision rule: we need events in a population in order to rule them out!
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237260/
https://www.ncbi.nlm.nih.gov/pubmed/28086985
http://dx.doi.org/10.1186/s13049-016-0346-9
work_keys_str_mv AT freundyonathan externalvalidationofaclinicaldecisionruleweneedeventsinapopulationinordertorulethemout
AT philipponannelaure externalvalidationofaclinicaldecisionruleweneedeventsinapopulationinordertorulethemout

Ejemplares similares