NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase

BACKGROUND: Aerobic glycolysis, a hallmark of cancer, is characterized by increased metabolism of glucose and production of lactate in normaxia. Recently, pyruvate kinase M2 (PKM2) has been identified as a key player for regulating aerobic glycolysis and promoting tumor cell proliferation and surviv...

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Detalles Bibliográficos
Autores principales: Gu, Zhimin, Xia, Jiliang, Xu, Hongwei, Frech, Ivana, Tricot, Guido, Zhan, Fenghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237262/
https://www.ncbi.nlm.nih.gov/pubmed/28086949
http://dx.doi.org/10.1186/s13045-017-0392-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237262/
https://www.ncbi.nlm.nih.gov/pubmed/28086949
http://dx.doi.org/10.1186/s13045-017-0392-4

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