Delta-like 4/Notch signaling promotes Apc(Min/+) tumor initiation through angiogenic and non-angiogenic related mechanisms

BACKGROUND: Delta like 4 (Dll4)/Notch signaling is a key regulator of tumor angiogenesis. Additionally, the role of Dll4 has been studied on tumor stem cells. However, as these cells are implicated in tumor angiogenesis, it is conceivable that the effect of Dll4 on these cells may be a consequence o...

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Detalles Bibliográficos
Autores principales: Badenes, Marina, Trindade, Alexandre, Pissarra, Hugo, Lopes-da-Costa, Luís, Duarte, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237288/
https://www.ncbi.nlm.nih.gov/pubmed/28086833
http://dx.doi.org/10.1186/s12885-016-3036-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237288/
https://www.ncbi.nlm.nih.gov/pubmed/28086833
http://dx.doi.org/10.1186/s12885-016-3036-0

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